Description
ABL(Y253H)
| 货号: 26154 |
| 规格: 100 μL |
| 基因符号: ABL1; ABL; JTK7; bcr-abl; c-ABL; p150; v-abl |
| 描述: Anti-ABL(Y253H) Mouse Monoclonal Antibody |
| 背景介绍: V-abl Abelson murine leukemia viral oncogene homolog 1 also known as ABL1, is a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, stress response and cell migration. Deficient in Abl can cause severe disease such as leukemia. |
| 免疫原: A synthetic peptide from the internal region of Abl which includes the mutation of Y253H, human origin |
| 经过测试的应用: ELISA, WB, IHC, IF |
| 推荐稀释比: ELISA: 1: 1000-1: 5000 WB: 1: 100-1: 1000 IF: 1: 50-1: 100 IHC: 1: 50-1: 100 |
| 浓度: 1 mg/ml |
| 宿主: Mouse |
| 形式: Liquid |
| 克隆性: Monoclonal |
| 亚型: IgG |
| 纯度: Purified from ascites |
| 防腐剂: No |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| 种属反应性: recognizes Abl Y253H, but not wildtype of vertebrates |
| 储存条件: Store at -20°C. Avoid repeated freezing and thawing |
蛋白质印迹:  Western blot analysis of recombinant Abl(Y253H) and wildtype proteins. Purified His-tagged Abl(Y253H) protein (amino acids 1-76, lane 2) and corresponding wild type protein (lane 1) were blotted with anti-ABL(Y253H) mouse monoclonal antibody (Cat. #26154). |
免疫荧光:  Immunofluorescence of cells expressing Abl proteins with anti-Abl(Y253H) antibody. HEK293T cells were transfected with pCDNA3-GFP-Abl (WT) plasmid (left column) or pCDNA3-GFP-Abl(Y253H) plasmid (right column), then fixed and stained with anti-ABL(Y253H) monoclonal antibody (Cat. #26154). |
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