Description
ALK(C1156Y) 单抗
| 货号: 26226 |
| 基因符号: ALK, CD246, NBLST3 |
| 描述: Anti-ALK(C1156Y) Mouse Monoclonal Antibody |
| 背景介绍: Anaplastic lymphoma kinase (ALK) also known as CD246 (cluster of differentiation 246) is a tyrosine kinase receptor that plays an important role in the development of the brain and nervous systems. Deficiencies in ALK, which most commonly as a fusion with other genes, are indicated in cancers. |
| 免疫原: A synthetic peptide from the internal region of ALK, which includes the mutation of C1156Y, human origin |
| 经过测试的应用: ELISA, WB, IF, IHC |
| 推荐稀释比: ELISA: 1: 1000-1: 5000 WB: 1: 500-1: 2000 IF: 1: 50-1: 100 IHC: 1: 50-1: 100 |
| 浓度: 1 mg/ml |
| 宿主: Mouse |
| 形式: Liquid |
| 克隆性: Monoclonal |
| 亚型: IgG |
| 纯度: Purified from ascites |
| 防腐剂: No |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| 种属反应性: Recognizes C1156Y mutant, but not wild-type ALK of vertebrates |
| 储存条件: Store at -20°C. Avoid repeated freezing and thawing |
蛋白质印迹: 
Western blot analysis of recombinant ALK(C1156Y) and wildtype proteins. Purified His-tagged ALK(C1156Y) protein (lane 2) and corresponding wildtype protein (lane 1) were blotted with Anti-ALK(C1156Y) monoclonal antibody (Cat. #26226).
免疫荧光:
Immunofluorescence of cells expressing ALK proteins with Anti-ALK(C1156Y) antibody. HEK293T cells were transfected with pCDNA3-GFP-ALK (WT) plasmid (left column) or pCDNA3-GFP-ALK(C1156Y) plasmid (right column), then fixed and stained with Anti-ALK(C1156Y) monoclonal antibody (Cat. #26226).
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