Description
cAMP
| 货号: 26002-1 | |
| 描述: Anti-cAMP Mouse Monoclonal Antibody | |
| 背景介绍: cAMP is a ubiquitous second messenger mediating cellular responses to various exogenous and endogenous signaling molecules. cAMP regulates physiological processes by activating protein kinases, gating specific ion channels, modulating cellular cyclic nucleotide concentrations through phosphodiesterases, and activating Epac (exchange protein directly activated by cAMP). The conversion of ATP to cAMP is catalyzed by adenylyl cyclases (ACs). The major family of ACs in mammals is the transmembrane ACs which have nine isoforms and could be activated by G protein Gs and/or Ca2+/calmodulin. There is also one soluble AC which could be modulated by bicarbonate and/or Ca2+. | |
| 免疫原: cAMP | |
| 经过测试的应用: ELISA, WB, IHC | |
| 推荐稀释比: ELISA 1:1000-1:5000 WB 1:500-1:2000 |
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| 浓度: 1 mg/ml | |
| 宿主: Mouse | |
| 形式: Liquid | |
| 克隆性: Monoclonal | |
| 亚型: IgG | |
| 纯度: Purified from ascites | |
| 防腐剂: No | |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol | |
| 储存条件: Store at -20°C. Avoid repeated freezing and thawing | |
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