Description
Gαq(Q209P)
| 货号: 26329 |
| 基因符号: GNAQ, CMC1, G-ALPHA-q, GAQ, SWS |
| 描述: Anti-GNAQ(Q209P) Mouse Monoclonal Antibody |
| 背景介绍: GNAQ is a protein that in humans encoded by the GNAQ gene. The GNAQ protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospholipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. |
| 免疫原: A synthetic peptide from the internal region of GNAQ, which includes the mutation of Q209P, human origin |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: ELISA: 1: 1000-1: 2000 WB: 1: 500-1: 1000 IHC: 1: 50-1: 100 |
| 浓度: 1 mg/ml |
| 宿主: Mouse |
| 形式: Liquid |
| 克隆性: Monoclonal |
| 亚型: IgG |
| 纯度: Purified from ascites |
| 防腐剂: No |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| 种属反应性: Recognizes Gαq(Q209P) mutant, but not wild-type GNAQ of vertebrates |
| 储存条件: Store at -20°C. Avoid repeated freezing and thawing |
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蛋白质印迹: 免疫荧光: :
Immunofluorescence of cells expressing GNAQ proteins with Anti-GNAQ(Q209P) antibody. HEK293T cells were transfected with pCDNA3-GFP-GNAQ(Q209P) plasmid, pCDNA3-GFP-GNAQ (WT) plasmid, pCDNA3-GFP-GNAQ (Q209L) plasmid or pCDNA3-GFP-GNAQ (Q209R) plasmid, then fixed and stained with Anti-GNAQ(Q209P) monoclonal antibody (Cat. #26329). |
Western blot analysis of recombinant GNAQ(Q209P) and wildtype proteins. Purified His-tagged GNAQ(Q209P) protein (lane2) and corresponding wild-type protein (lane1) were blotted with Anti-GNAQ(Q209P) monoclonal antibody (Cat. #26329).
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