Description
KIT(D820E) 单抗
| 货号: 26274 |
| 基因符号: C-Kit; CD117; KIT; PBT; SCFR |
| 描述: Anti-KIT(D820E) Mouse Monoclonal Antibody |
| 背景介绍: Tyrosine-protein kinase Kit, also known as proto-oncogene c-Kit or CD117 or Mast/stem cell growth factor receptor (SCFR), is a receptor tyrosine kinase protein that in humans is encoded by the KIT gene. Activating mutations in this gene are associated with gastrointestinal stromal tumors, testicular seminoma, mast cell disease, melanoma, acute myeloid leukemia, while inactivating mutations are associated with the genetic defect piebaldism. |
| 免疫原: A synthetic peptide from the internal region of KIT, which includes the mutation of D820E, human origin |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: ELISA: 1: 1000-1: 5000 WB: 1: 500-1: 1000 IHC: 1: 50-1: 100 |
| 浓度: 1 mg/ml |
| 宿主: Mouse |
| 形式: Liquid |
| 克隆性: Monoclonal |
| 亚型: IgG |
| 纯度: Purified from ascites |
| 防腐剂: No |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| 种属反应性: Recognizes D820E mutant, but not wild-type KIT of vertebrates |
| 储存条件: Store at -20°C. Avoid repeated freezing and thawing |
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蛋白质印迹: Purified His-tagged KIT (D820E) protein (lane 1) and corresponding wild-type protein (lane 2) were blotted with Anti-KIT(D820E) monoclonal antibody (Cat. #26274). 免疫荧光: HEK293T cells were transfected with pCDNA3-GFP-KIT (WT) plasmid (left column) or pCDNA3-GFP-KIT (D820E) plasmid (right column), then fixed and stained with anti- KIT (D820E) monoclonal antibody (Cat. #26274). |
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